Parents and caregivers can drive data collection by contributing to the largest dataset on Angelman syndrome by entering details of their loved one/s diagnosis, medical history, development, and more in a series of online modules. The Global Angelman Syndrome Registry is a tool for understanding developmental progress, medication, and seizure management, but more importantly, it provides an invaluable resource to advance the search for therapeutics. We ask that you complete the registration and update it annually as a part of moving us toward meaningful treatments.